Biomanufacturing uses biological resources to create materials that have numerous medical and industrial applications. This cutting-edge field enables sustainable production methods and innovative solutions to some of the world's biggest challenges, from medicine to environmental sustainability. The biomanufactured products are found in microbes, animal, and plant cells that are grown in specialized equipment called bioreactors. These are prime examples of how biomanufacturing companies are reshaping modern industries.
Here are some of the companies making a significant impact in this field in 2025:
This US-based startup uses its proprietary platform to radically increase the speed and scaling of mammalian cell line discovery. 64xBio's VectorSelect™ platform exponentially increases experimental output using DNA library synthesis, next-generation sequencing, and machine learning. This platform has revolutionized the biomanufacturing of viral vectors by addressing critical bottlenecks in cell line development.
The company's technology enables the discovery of optimized and previously unattainable cell lines, reducing time-to-market for life-saving cell and gene therapies. This innovation is especially critical for addressing growing demands in precision medicine and advanced therapeutics. As one of the leading bioprocessing companies, it ensures scalable solutions for the biotech sector. The company’s work contributes to the rapid advancements in biomanufacturing, showcasing the transformative power of integrating AI with biosciences.
Cellibre is a US-based startup specializing in engineering cells to function as biomanufacturing units for a range of high-value products, from cannabinoids to pharmaceutical ingredients. By leveraging synthetic biology and precision fermentation, Cellibre creates efficient, scalable, and sustainable production methods.
Their platform enables cost-effective production of complex molecules, making them a leader in providing alternatives to traditional chemical synthesis methods, which are often resource-intensive and environmentally harmful. In 2025, Cellibre continues to stand out for its ability to bridge the gap between sustainable practices and commercial scalability, making it an essential player in the field of industrial biomanufacturing.
This startup from the US helps its customers accelerate bioprocess development by offering them bioreactors to run their experiments. Customers can save money by not investing in expensive bioreactor equipment and also speed up bringing their goods to the market. The experiments are designed by customers and then carried out by the experts at Culture Biosciences in their state-of-the-art bioreactors.
Culture Biosciences also offers an intuitive online dashboard where customers can monitor their experiments and analyze data in real-time. This seamless integration of hardware and software accelerates research and development for biomanufacturing companies.
Culture Biosciences uses Scispot to digitize and automate their media preparation workflows end to end while maintaining the full audit trail. It leverages Scispot’s built-in template library and inventory automation module to standardize media preparation and automate their inventory consumption and production. This makes it one of the top manufacturing startups in the field. Culture’s approach exemplifies how cloud-based solutions are revolutionizing bioprocessing and providing accessible tools for biotech innovations.
Helaina, a US-based startup, uses fermentation technology to create bioidentical human milk proteins, redefining the infant nutrition space. By leveraging biomanufacturing, Helaina ensures high-quality, scalable production of essential nutrients for babies, promoting healthier alternatives to traditional infant formula.
This breakthrough technology addresses global nutritional challenges by offering an ethical, sustainable, and scientifically advanced solution to infant nutrition. Helaina's innovations extend beyond infant formula, with potential applications in medical nutrition and personalized dietary products. It stands as a prime example of biomanufacturing examples that impact daily life. By integrating novel bioprocessing techniques, Helaina is set to expand its footprint into medical-grade nutrition and customized healthcare solutions in 2025.
Debut Biotechnology is a US-based startup that uses a novel platform for cell-free biomanufacturing. This platform helps to overcome traditional biomanufacturing barriers such as low yields and excess waste management. By using optimized enzymes and cellular machinery outside of living cells, Debut’s technology enables higher production rates and shorter developmental times.
The company's approach eliminates the constraints of traditional bioreactors, offering faster, cleaner, and more flexible manufacturing methods. Their work has applications across pharmaceuticals, cosmetics, and food industries, positioning them as pioneers in sustainable and efficient bio tech manufacturing. In 2025, Debut’s advancements are further driving innovation in precision manufacturing, offering scalable alternatives to traditional chemical processes.
Lab Management Software for Modern Biomanufacturing Companies: Scispot
Scispot has become the primary lab management software of choice for numerous biotech companies, including biomanufacturing companies. The platform is uniquely designed to cater to the fast-paced and innovation-driven environment of biomanufacturing labs.
Scispot creates a connected digital replica of these innovative bioscience companies. It centralizes their company-wide data, templatizes routine research, and automates non-scientific tasks. By integrating inventory management, sample tracking, and workflow automation, Scispot reduces operational inefficiencies and boosts productivity.
Modern biotech companies use Scispot’s operating platform to manage their research projects, inventory, samples, and partners all in one spot. As of 2025, Scispot continues to lead in providing modern digital infrastructure for the biotech and biomanufacturing industries.
Request a demo to learn how you can accelerate your research using Scispot.
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